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KMID : 0191119940090030213
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Journal of Korean Medical Science
1994 Volume.9 No. 3 p.213 ~ p.217
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Antigenic relationship between mugwort and ragweed pollens by crossed immunoelectrophoresis
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Park HS
Kim MJ/Moon HB
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Abstract
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Mugwort and ragweed pollens have been considered as important respiratory allergens in
Korea. These two pollens are abundant in the air of Seoul from August through October. Many ragweed-sensitive patients have shown concurrent sensitivities to mugwort pollen. However the antigenic relationship between these two pollens has not been clarified. To observe the cross-reactivity between them, we developed polyclonal anti-mugwort and anti-ragweed antibodies by immunization on New Zealand white rabbits, and performed crossed immunoelectrophoresis(CIE) with two pollen extracts. Five precipitation lines were formed by mugwort and anti-mugwort antibody.
One precipitation line was formed by ragweed and anti-ragweed antibody. There was no reaction from mugwort and anti-ragweed antibody, and from ragweed and anti-mugwort antibody. These results indicate that there is no cross-antigenicity between mugwort and ragweed pollens.
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KEYWORD
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